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. 2020 Jan 14;17(2):191–206. doi: 10.7150/ijms.39261

Table 6.

GO enrichment analysis showing the significant molecular functions (MF) of the top 500 hypomethylated promoters.

GOMFID P-value Odds ratio ExpCount Count Size Term
GO:0036374 0 105.3038 0.0575 3 6 glutathione hydrolase activity
GO:0047844 0.0019 41.8516 0.0671 2 7 deoxycytidine deaminase activity
GO:0000979 0.0045 9.855 0.3354 3 35 RNA polymerase II core promoter sequence-specific DNA binding
GO:0004126 0.0057 20.9195 0.115 2 12 cytidine deaminase activity
GO:0050681 0.0075 8.0828 0.4025 3 42 androgen receptor binding
GO:0031492 0.0091 7.5041 0.4312 3 45 nucleosomal DNA binding
GO:0003940 0.0096 Inf 0.0096 1 1 L-iduronidase activity
GO:0004326 0.0096 Inf 0.0096 1 1 tetrahydrofolylpolyglutamate synthase activity
GO:0004441 0.0096 Inf 0.0096 1 1 inositol-1,4-bisphosphate 1-phosphatase activity
GO:0008725 0.0096 Inf 0.0096 1 1 DNA-3-methyladenine glycosylase activity
GO:0008829 0.0096 Inf 0.0096 1 1 dCTP deaminase activity
GO:0008841 0.0096 Inf 0.0096 1 1 dihydrofolate synthase activity
GO:0031962 0.0096 Inf 0.0096 1 1 mineralocorticoid receptor binding
GO:0034512 0.0096 Inf 0.0096 1 1 box C/D snoRNA binding
GO:0043916 0.0096 Inf 0.0096 1 1 DNA-7-methylguanine glycosylase activity
GO:0050649 0.0096 Inf 0.0096 1 1 testosterone 6-beta-hydroxylase activity
GO:0052821 0.0096 Inf 0.0096 1 1 DNA-7-methyladenine glycosylase activity
GO:0052822 0.0096 Inf 0.0096 1 1 DNA-3-methylguanine glycosylase activity
GO:0052829 0.0096 Inf 0.0096 1 1 inositol-1,3,4-trisphosphate 1-phosphatase activity
GO:0086038 0.0096 Inf 0.0096 1 1 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
GO:0031625 0.0096 2.8578 2.9417 8 307 ubiquitin protein ligase binding