Table 4.
Cox risk model analysis of prognostic influencing factor for uterine sarcoma
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR(95%CI) | P-value | HR(95%CI) | P-value | |
| Histological types | 0.001 | <0.001 | ||
| LG-ESS | 1(referent) | 1(referent) | ||
| HG-ESS | 3.626(1.543-8.518) | 0.003 | 5.969(2.359-15.103) | <0.001 |
| UUS | 8.019(3.238-19.862) | <0.001 | 18.356(6.043-55.759) | <0.001 |
| LMS | 1.542(0.724-3.284) | 0.261 | 2.294(1.011-5.203) | 0.047 |
| AS | 1.707(0.486-5.999) | 0.404 | 2.240(0.479-10.472) | 0.305 |
| FIGO stage | <0.001 | <0.001 | ||
| Ⅰ | 1(referent) | 1(referent) | ||
| Ⅱ | 1.876(0.563-6.258) | 0.306 | 3.841(1.097-13.442) | 0.035 |
| Ⅲ | 3.170(1.356-7.409) | 0.008 | 3.573(1.468-8.695) | 0.005 |
| Ⅳ | 8.676(4.276-17.604) | <0.001 | 14.451(6.359-32.841) | <0.001 |
| Age(years) | 0.512 | |||
| <50 | 1(referent) | |||
| ≥50 | 1.220(0.673-2.213) | |||
| Menstrual status | 0.021 | |||
| premenopausal | 1(referent) | |||
| postmenopausal | 1.974(1.106-3.522) | |||
| Tumor size(cm) | 0.316 | |||
| ≤5cm | 1(referent) | |||
| >5cm | 1.400(0.725-2.705) | |||
| NLR | 0.008 | |||
| <3.61 | 1(referent) | |||
| ≥3.61 | 2.265(1.243-4.218) | |||
LG-ESS: low-grade endometrial stromal sarcoma; HG-ESS: high-grade endometrial stromal sarcoma; UUS: undifferentiated uterine sarcoma; LMS: leiomyosarcoma; AS: adenosarcoma; HR: hazard ratio; CI: confidence interval; NLR: neutrophil/lymphocyte ratio.