Figure 2.

Gene and protein alteration of B7 family members in gastric cancer. A. The mutation rate of B7 family members in gastric cancer. B. Alteration frequency of B7 family genes in gastric cancer, including mutations, amplification, mRNA overexpression and multiple changes were analyzed from the TCGA database and studied in cBioPortal. 478 gastric cancer samples were used for this analysis, and about 14% samples (66/478) showed B7 family alteration. C. Changes in protein structure of B7 family members. SRCSTAD: Signet ring cell carcinoma of the stomach; Tubular stomach adenocarcinoma: TSTAD; Stomach adenocarcinoma: STAD; Diffuse type stomach adenocarcinoma: DTSTAD; Mucinous stomach adenocarcinoma: MSTAD