Table 1.
Relationship between expression levels of CHIP or Gal1 and clinicopathological features in CRC patients
| Variables | CHIP | Gal1 | |||||
|---|---|---|---|---|---|---|---|
| n=465 cases | n=465 cases | ||||||
| low (%) | high (%) | Pa | low (%) | high (%) | Pa | ||
| All patients | 188 (40.4) | 277 (59.6) | 291 (62.6) | 174 (37.4) | |||
| Age (years) | 0.117 | 0.137 | |||||
| ≤ 65 | 100 (37.9) | 164 (62.1) | 172 (64.9) | 93 (35.1) | |||
| >65 | 88 (46.8) | 113 (53.2) | 119 (59.5) | 81 (40.5) | |||
| Gender | 0.08 | 0.315 | |||||
| Males | 105 (37.6) | 174 (62.4) | 171 (61.5) | 107 (38.5) | |||
| Females | 83 (44.6) | 103 (55.4) | 120 (64.2) | 67 (35.8) | |||
| Pathological classificationb | 0.039 | 0.007 | |||||
| I | 3 (60.0) | 2 (40.0) | 3 (60.0) | 2 (40.0) | |||
| II | 162 (38.7) | 257 (61.3) | 270 (64.4) | 149 (35.6) | |||
| III | 21 (58.3) | 15(41.7) | 14 (38.9) | 22(61.1) | |||
| Depth of invasionb | 0.064 | <0.001 | |||||
| T1/T2 | 49 (47.6) | 54 (52.4) | 86 (84.3) | 16 (15.7) | |||
| T3/T4 | 138 (38.5) | 220 (61.5) | 201 (56.0) | 158 (44.0) | |||
| Lymph node metastasisb | <0.001 | <0.001 | |||||
| N0 | 84 (30.7) | 190 (69.3) | 200 (73.3) | 73 (26.7) | |||
| N1/N2 | 103 (54.8) | 85 (45.2) | 88 (46.6) | 101 (53.4) | |||
| TNM stageb | <0.001 | <0.001 | |||||
| I | 39 (44.3) | 49 (55.7) | 73 (83.9) | 14 (16.1) | |||
| II | 41 (23.2) | 136 (76.8) | 124 (70.1) | 53 (29.9) | |||
| III | 94 (52.8) | 84 (47.2) | 88 (49.2) | 91 (50.8) | |||
| IV | 13 (76.5) | 4 (23.5) | 2 (11.8) | 15 (88.2) | |||
| Tumor diameterb | 0.429 | 0.052 | |||||
| ≤ 5 cm | 152 (40.6) | 222 (59.4) | 241 (64.4) | 133 (35.6) | |||
| >5 cm | 35 (38.9) | 55 (61.1) | 49 (54.4) | 41 (45.6) | |||
| Distant metastasis | 0.003 | <0.001 | |||||
| M0 | 174(39.0) | 272(61.0) | 289(64.8) | 157(35.2) | |||
| M1 | 14(73.7) | 5(26.3) | 2(10.5) | 17(89.5) | |||
a Two-sided Fisher's exact tests
b Some patients missing these clinical pathological parameters