Age at diagnosis |
|
Mean (SD), y |
61.7 (14.0) |
Median (range), y |
64 (41-80) |
Time to diagnosis, mean (range) |
3.7 y (1 mo-20 y) |
Race |
|
White |
25 (93) |
African American |
2 (7) |
Site of lichen planus disease |
|
Vulvar mucosa |
27 (100) |
Vulvar mucosa only |
7 (26) |
Vaginal mucosa |
6 (22) |
Oropharyngeal mucosa |
19 (70) |
Skin |
5 (19) |
Disease symptoms |
|
Pruritus |
11 (41) |
Burning sensation |
11 (41) |
Pain |
8 (29) |
Erosions |
|
Erythema |
8 (30) |
Wickham striae |
7 (26) |
Scarring |
7 (26) |
Erythema and Wickham striae |
5 (19) |
Biopsy site |
|
Oral |
8 (30) |
Vulvar |
6 (22) |
Cutaneous |
4 (15) |
Vulvar (previous physician) |
5 (19) |
Oral (previous physician) |
2 (7) |
Cutaneous (previous physician) |
1 (4) |
Unspecified |
1 (4) |
Histopathologic characteristics |
|
Bandlike infiltrate at dermoepidermal junction |
11 (41) |
Foci of lichenoid inflammation |
5 (19) |
Unspecific inflammation |
4 (15) |
Ulceration and lichenoid mucositis |
3 (11) |
Lichenoid mucositis |
3 (11) |
Unspecified |
1 (4) |
Criteria for diagnosis |
|
Clinical and histologic |
26 (96) |
Clinical |
1 (4) |
Other conditions |
|
Vulvodynia |
4 (15) |
Thyroid disease |
2 (7) |
Psoriasis |
1 (4) |
Rosacea conjunctivitis |
1 (4) |
Fibromyalgia |
1 (4) |
Herpes simplex virus type 1/2 |
1 (4) |
Previous medications |
|
Clobetasol |
8 (30) |
Prednisone |
6 (22) |
Methotrexate |
5 (19) |
Hydroxychloroquine |
4 (15) |
Betamethasone |
3 (11) |
Clotrimazole |
3 (11) |
Lidocaine |
2 (7) |
Mycophenolate mofetil |
2 (7) |
Fluocinonide |
2 (7) |
Conjugated estrogens |
2 (7) |
Acitretin |
1 (4) |
Triamcinolone |
1 (4) |
Topical cyclosporine |
1 (4) |
Hydrocortisone suppository |
1 (4) |