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. 2020 Jan 8;77(5):1–11. doi: 10.1001/jamapsychiatry.2019.4188

Figure 1. Conditional Quantile-Quantile Plots.

Figure 1.

A, C, and E, Conditional quantile-quantile plots of nominal vs empirical body mass index (BMI) −log10 P values (corrected for inflation) below the standard genome-wide association study threshold of P < 5 × 10−8 as a function of the significance of the association with schizophrenia (SCZ), bipolar disorder (BIP), and major depression (MD) at the level of P ≤ .10, P ≤ .01, and P ≤ .001, respectively. B, D, and F, Conditional quantile-quantile plots of nominal vs empirical SCZ, BIP, and MD −log10 P values (corrected for inflation) below the standard genome-wide association study threshold of P < 5 × 10−8 as a function of the significance of the association with BMI, at the level of P ≤ .10, P ≤ .01, and P ≤ .001, respectively. The dashed line indicates the null hypothesis. SNP indicates single-nucleotide polymorphism.