Table 1. Baseline characteristics of ICC patients with different expression of UBE2T (N = 401).
Characteristics | Low (N = 288) | High (N = 113) | P value |
---|---|---|---|
Age, years | 53.58 ± 11.14 | 52.82 ± 9.83 | 0.688 |
Sex | 0.618 | ||
Male | 211(73.3%) | 80(70.8%) | |
Female | 77(26.7%) | 33(29.2%) | |
AFP, ng/mL | 81.69 ± 236.65 | 112.83 ± 286.36 | 0.069 |
CEA, ng/mL | 14.17 ± 84.30 | 14.76 ± 94.78 | 0.920 |
CA199, ng/mL | 169.47 ± 274.57 | 140.65 ± 221.52 | 0.692 |
TBIL, µmol/L | 15.58 ± 15.57 | 24.66 ± 55.93 | 0.009 |
ALB, g/L | 42.15 ± 4.27 | 41.23 ± 4.67 | 0.144 |
ALT, U/L | 47.55 ± 67.75 | 43.06 ± 44.44 | 0.665 |
GGT, U/L | 108.22 ± 129.31 | 155.61 ± 256.95 | 0.060 |
ALP, U/L | 122.85 ± 96.98 | 130.06 ± 105.59 | 0.377 |
HBsAg | 0.085 | ||
Positive | 165(57.3%) | 54(47.8%) | |
Negative | 123(42.7%) | 59(52.2%) | |
Tumor size, cm | 6.15 ± 3.35 | 7.33 ± 3.56 | 0.002 |
Tumor number | 0.070 | ||
Single | 235(81.6%) | 83(73.5%) | |
Multiple | 53(18.4%) | 30(26.5%) | |
Surgical margin | 0.776 | ||
<1 cm | 213(74.0%) | 82(72.6%) | |
≥1 cm | 75(26.0%) | 31(27.4%) | |
Liver cirrhosis | 0.795 | ||
Yes | 75(26.0%) | 28(24.8%) | |
No | 213(74.0%) | 85(75.2%) | |
MVI | 0.018 | ||
Positive | 53(18.4%) | 33(29.2%) | |
Negative | 235(81.6%) | 80(70.8%) | |
TNM | 0.924 | ||
I–II | 241(83.7%) | 95(84.1%) | |
III–IV | 47(16.3%) | 18(15.9%) |
Notes.
- ICC
- intrahepatic cholangiocarcinoma
- AFP
- alpha fetoprotein
- CEA
- carcinoembryonic antigen
- CA199
- carbohydrate antigen 19-9
- TBIL
- total bilirubin
- ALB
- albumin
- ALT
- alanine aminotransferase
- GGT
- gamma glutamyltransferase
- ALP
- alkaline phosphatase
- HBsAg
- hepatitis B surface antigen
- MVI
- microvascular invasion, TNM tumor-node-metastasis