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. Author manuscript; available in PMC: 2020 Jan 30.
Published in final edited form as: ACS Nano. 2019 Mar 26;13(4):4443–4454. doi: 10.1021/acsnano.8b09683

Figure 8.

Figure 8.

Characterization of Rev-CD encapsulated PP7-PP7-OVA particles. (A) Electrophoretic analysis: purified particles showing PP7-PP7-OVA1, PP7-PP7-OVA2, and Rev-CD bands. (B) TEM; images are indistinguishable from those of PP7-PP7-OVA1 and PP7-PP7-OVA2 without enzyme packaged. (C) Kinetic analysis, plotted on a per-enzyme basis, of the conversion of 5-FC to 5-FU catalyzed by the indicated forms of cytosine deaminase. Solid curves show the best fit using the Michaelis–Menten equation. The @ symbol designates the encapsidated enzyme.