Table 2.
Exposure method | Peat | Eucalyptus | Oak | ||||
---|---|---|---|---|---|---|---|
Smoldering | Flaming | Smoldering | Flaming | Smoldering | Flaming | ||
Deposited PM mass | |||||||
Aspiration1) | 81 | 81 | 81 | 81 | 81 | 81 | |
Inhalation2) | 65.8±1.8 | 6.1±0.2 | 60.9±2.0 | 5.5±0.3 | 97.1±9.7 | 9.2±0.7 | |
Lung toxicity potency | |||||||
Aspiration3) | 4 h | 39±14* | 294±173* | 105±33* | 209±52* | 27±12 | 88±52* |
24 h | 41±12 | 846±274* | 94±35* | 782±527* | 70±52 | 17±7 | |
Inhalation4) | 4h | 41±7* | 454±78* | 64±9* | 321±70 | 25±5 | 203±44 |
24h | 68±15 | 1,208±332* | 53±18 | 589±144* | 21±6 | 333±59 |
Note: Error ranges represent standard error of the mean (SEM)
Deposited PM mass = PM deposition fraction in the respiratory tract (Foster et al. 2001) × PM dose (Kim et al. 2018)
Deposited PM mass = PM deposition fraction in the respiratory tract (Figure 7A) × PM dose (Table 1) × Total respiratory volume (Table S4)
Lung toxicity potency = Neutrophil counts (Kim et al. 2018) / Deposited PM mass
Lung toxicity potency = Neutrophil counts (Figure 5B) / Deposited PM mass
These values were statistically significant from the respective negative control groups.