Horne 1988.
Methods | RCT, D‐B, 8 weeks, ITT possible for dichotomic outcomes | |
Participants | 81 Bulimia DSM‐III, 3 episodes/week/6 months, BN > 1year, not depressed, 18‐55 years old, mean 26(b) and 27(PL), weight=80‐130% desirable body weight, mean 57 (b), 60 (pl), duration of BN=6.5 years, binges/week= 12(b)/8.5(pl), HDRS baseline 10.6, patients seeking treatment and advertisement | |
Interventions | Bupropion 450mg versus placebo, no other concomitant ttt (no psychotherapy) | |
Outcomes | Remission Clinical improvement Drop‐outs dus to adverse events and any cause | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |