Skip to main content
. 2003 Oct 20;2003(4):CD003391. doi: 10.1002/14651858.CD003391

Horne 1988.

Methods RCT, D‐B, 8 weeks, ITT possible for dichotomic outcomes
Participants 81 Bulimia DSM‐III, 3 episodes/week/6 months, BN > 1year, not depressed, 18‐55 years old, mean 26(b) and 27(PL), weight=80‐130% desirable body weight, mean 57 (b), 60 (pl), duration of BN=6.5 years, binges/week= 12(b)/8.5(pl), HDRS baseline 10.6, patients seeking treatment and advertisement
Interventions Bupropion 450mg versus placebo, no other concomitant ttt (no psychotherapy)
Outcomes Remission 
 Clinical improvement 
 Drop‐outs dus to adverse events and any cause
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear