| Methods |
RCT, 10 weeks, physicians responsible for medication management were blind to randomization. |
| Participants |
Bulimia DSM‐III, 3 episodes/week/6 months, patients being evaluated in ED clinic and advertisements. Age 18‐40, mean 24, female, 80‐120% ideal body weight, mean 107%, duration of illness 6.5 years,binges/week baseline=7,3(i)/ 8,0(pl)/ 9,2(pt)/ 8.4(comb).HDRS baseline=11 |
| Interventions |
Imipramine initial dose 50 mg, increments to 200 mg for 2 weeks, maintained for 2 weeks, if necessary 300 mg.CBT= 3 phases. 1= 2 hour sessions for each week 2 weeks: mael planning and CBT techniques. 2=arttempt to interrupt bulimic behaviors begin eating regular meals, use of CBT techniques,5 nights a week, 3 hour sessions, then 2 sessions/week (lecture+diner+psychotherapy). 3= last month: 1 and half hour sessions, exposure and relapse prevention |
| Outcomes |
Relapse
Drop‐outs due to any cause |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
