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. 2003 Apr 22;2003(2):CD003158. doi: 10.1002/14651858.CD003158

Herrmann 1990.

Methods Randomized double blind placebo controlled study
Participants Country: Germany 
 Multicentre 
 Selection criteria: 
 mild to moderate cognitive decline corresponding to stages 3 or 4 on the Global Deterioration Scale (80% GDS stage 3) 
 230 male and female patients age 60‐80 years
Interventions 1. ALC 1.5g/day for 12 weeks 
 2. Placebo for 12 weeks
Outcomes CGI‐C, NGDAS, modified digit symbol substitution test.
Notes Analysed completers, not intention to treat