Adler 1987 |
Allocation: not randomised. |
Adler 1988 |
Allocation: not randomised. |
Adler 1993 |
Allocation: randomised.
Participants: people with chronic schizophrenia, schizoaffective disorder, major depression with psychosis.
Interventions: propanolol versus benztropine versus placebo.
Outcomes: no usable data, 9 of 28 participants were given concomitant benzodiazepines, no seperate data available. |
Friss 1983 |
Allocation: randomised, cross‐over design.
Participants: people whose diagnosis was not specified, suffering from neuroleptic‐induced akathisia.
Interventions: valproate versus biperiden versus placebo.
Outcomes: no data about allocation in first period. Dr Gerlach (author) contacted and replied promptly; data were destroyed and no more information is available. |
Gagrat 1978 |
Allocation: randomised.
Participants: people with psychotic disorders, suffering from neuroleptic‐induced akathisia.
Interventions: benzodiazepine versus diphenhydramine, none versus placebo. |
Hermesh 1988 |
Allocation: not randomised, not controlled clinical trial. |
Hirose 2000 |
Allocation: unclear.
Participants: people with psychotic disorders, suffering from neuroleptic‐induced akathisia.
Interventions: biperiden at different dosages. |
Horiguchi 1992 |
Allocation: randomised.
Participants: people with schizophrenia, suffering from neuroleptic‐induced akathisia.
Interventions: benzodiazepine versus anticholinergic, none versus placebo. |
Neu 1972 |
Allocation: randomised.
Participants: people with psychotic disorders, suffering from neuroleptic‐induced akathisia.
Interventions: anticholinergic versus anticholinergic, none versus placebo. |
Sachdev 1993 |
Allocation: randomised.
Participants: people with schizophrenia, suffering from neuroleptic‐induced akathisia.
Interventions: benztropine (iv) versus propranolol (iv) versus placebo (iv).
Outcomes: no usable data, two of the 6 participants were taking benzodiazepines, no separate data available. |
Zeng 1995 |
Allocation: unclear.
Participants: people suffering from neuroleptic‐induced akathisia.
Interventions: dexetimide versus benzhexolum, no placebo group. |