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. 2019 Dec 17;24(2):2004–2012. doi: 10.1111/jcmm.14899

Figure 6.

Figure 6

miR‐18a inhibited autophagy in RAW264.7 macrophages by ATM‐AMPK pathway. A, The RAW264.7 cells were infected with Mtb or without Mtb and then transfected with ATM siRNA or ATM siRNA NC. The expression of LC3‐II in RAW264.7 macrophages was determined by Western blot. B, The RAW264.7 cells were infected with Mtb or without Mtb and then transfected with miR‐18a inhibitor or ATM siRNA. The expression of LC3‐II in RAW264.7 macrophages was determined by Western blot. C, The RAW264.7 cells were infected with Mtb or without Mtb and then transfected with miR‐18a inhibitor or ATM siRNA. The expression of p‐AMPK in RAW264.7 macrophages was determined by Western blot. D, The RAW264.7 cells were infected with Mtb or without Mtb and then transfected with miR‐18a inhibitor or ATM siRNA. The expression of p‐mTOR in RAW264.7 macrophages was determined by Western blot. Data represent the means ± SD from three independent experiments. **P < .01, *P < .05