Table 2. Examples of Patient-Specific Clinical and Diagnostic Guidance^a.

Patient-Specific Guidance	Action Required
Interpreting abnormal LDL cholesterol results in type 2 diabetes based on the LDL level and the presence of arterial atherosclerotic disease	Consider drug, consider test
Suggesting hemochromatosis based on increased ferritin, iron, or transferrin saturation results	Consider diagnosis
Recommending to avoid a drug included in the European list of potentially inappropriate medications for an elderly patient32	Reconsider drug
Providing advice for prevention of constipation when initiating a strong opioid	Consider drug, change drug
Reminding of missing or outdated follow-up tests for a patient receiving amiodarone hydrochloride	Consider test, consider imaging
Recommending to document or investigate the reason for a decreased glomerular filtration rate in case no structured documentation is found	Missing diagnosis, consider test

Abbreviation: LDL, low-density lipoprotein.

^aClassified based on the Evidence-Based Medicine Electronic Decision Support reminder classification thesaurus, with actions potentially required to resolve the detected problem. Examples were selected among 25 top-ranked frequently generated and resolved guidance messages.