Summary of findings 2. Trauma‐focused CBT/Exposure therapy compared with non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults.
| Trauma‐focused CBT/Exposure therapy compared with non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults | ||||||
| Patient or population: Adults with PTSD for at least 3 months Settings: Primary care, community, outpatient Intervention: Trauma‐focused CBT/Exposure therapy Comparison: non‐Trauma‐focused CBT | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Non‐TFCBT | Trauma Focused CBT/ Exposure Therapy | |||||
| Severity of PTSD Symptoms ‐ Clinician‐rated | The mean severity of PTSD symptoms ‐ clinician‐rated in the intervention groups was 0.27 standard deviations lower (0.63 lower to 0.10 higher) | 267 (7 studies) | ⊕⊝⊝⊝ very low1,2 | |||
| Leaving the study early for any reason | Study population | RR 1.19 (0.71 to 2.00) | 312 (7 studies) | ⊕⊝⊝⊝ very low1,2,3 | ||
| 154 per 1000 | 183 per 1000 (109 to 308) | |||||
| Moderate | ||||||
| 154 per 1000 | 183 per 1000 (109 to 308) | |||||
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; | ||||||
| GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. | ||||||
1Some studies were judged to pose a high risk of bias 2Unexplained heterogeneity 3Small sample sizes