Summary of findings 6. EMDR compared with non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults.
EMDR compared with non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults | ||||||
Patient or population: Adults with PTSD for at least 3 months Settings: Primary care, community, outpatient Intervention: Eye movement desensitization and reprocessing (EMDR) Comparison: non‐trauma‐focused CBT | ||||||
Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
Assumed risk | Corresponding risk | |||||
Non‐TFCBT | EMDR | |||||
Severity of PTSD symptoms ‐ Clinician‐rated | The mean severity of PTSD symptoms ‐ clinician in the intervention groups was | 0.35 standard deviations lower (0.90 lower to 0.19 higher) | 53 (2 studies) | ⊕⊝⊝⊝ very low1,2 | ||
Leaving the study early for any reason | Study population | RR 1.03 (0.37 to 2.88) | 84 (3 studies) | ⊕⊝⊝⊝ very low1,2 | ||
140 per 1000 | 144 per 1000 (46 to 367) | |||||
Moderate | ||||||
91 per 1000 | 94 per 1000 (29 to 264) | |||||
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: risk ratio; | ||||||
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. |
1Studies reported insufficient information to judge risk of bias 2Small sample sizes. Only two studies.