Summary of findings 12. Other therapies compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults.
Other therapies compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults | ||||||
Patient or population: Adults with PTSD for at least 3 months Settings: Primary care, community, outpatient Intervention: Other therapies Comparison: Waitlist/Usual Care | ||||||
Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
Assumed risk | Corresponding risk | |||||
Waitlist/Usual Care | Other therapies | |||||
Severity of PTSD symptoms ‐ Clinician | The mean severity of PTSD symptoms ‐ clinician in the intervention groups was 0.58 standard deviations lower (0.96 to 0.20 lower) | 112 (3 studies) | ⊕⊝⊝⊝ very low1 | |||
Leaving the study early due to any reason | Study population | RR 2.45 (0.99 to 6.10) | 211 (4 studies) | ⊕⊝⊝⊝ very low1,2 | ||
74 per 1000 | 181 per 1000 (73 to 452) | |||||
Moderate | ||||||
72 per 1000 | 176 per 1000 (71 to 439) | |||||
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; | ||||||
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. |
1Small sample sizes 2Studies were judged to pose a low/unclear risk of bias