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. 2013 Dec 13;2013(12):CD003388. doi: 10.1002/14651858.CD003388.pub4

Summary of findings 12. Other therapies compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults.

Other therapies compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Patient or population: Adults with PTSD for at least 3 months
 Settings: Primary care, community, outpatient
 Intervention: Other therapies
 Comparison: Waitlist/Usual Care
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) No of Participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
Waitlist/Usual Care Other therapies
Severity of PTSD symptoms ‐ Clinician   The mean severity of PTSD symptoms ‐ clinician in the intervention groups was
 0.58 standard deviations lower 
 (0.96 to 0.20 lower)   112
 (3 studies) ⊕⊝⊝⊝
 very low1  
Leaving the study early due to any reason Study population RR 2.45 
 (0.99 to 6.10) 211
 (4 studies) ⊕⊝⊝⊝
 very low1,2  
74 per 1000 181 per 1000 
 (73 to 452)
Moderate
72 per 1000 176 per 1000 
 (71 to 439)
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; RR: Risk ratio;
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

1Small sample sizes
 2Studies were judged to pose a low/unclear risk of bias