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. 2013 Dec 13;2013(12):CD003388. doi: 10.1002/14651858.CD003388.pub4

Cooper 1989.

Methods Randomised controlled trial
Participants 16 male Vietnam War veterans in the USA. All DSM‐III PTSD
Interventions 6 ‐ 14 90‐minute flooding sessions plus standard treatment (n = 8) vs standard treatment (n = 8)
Outcomes STAI, BDI
Notes No information was provided with regards to the therapists delivering treatment or any measures of treatment adherence.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Quote: "Efforts were made to preclude bias in assessment by maintaining as nearly random a procedure as possible"
Comment: There were no details of the method of sequence generation, but the authors indicate that it was not entirely random.
Allocation concealment (selection bias) High risk Quote: "In all cases group assignment was pre‐decided before the participant agreed to participate...there were three exceptions to the rule of pre‐determined random assignment"
Comment: Allocation does not seem to have been concealed.
Incomplete outcome data (attrition bias) 
 All outcomes High risk All 16 participants provided posttreatment data, but 2 were removed from the analysis of data from the experimental group due to not completing therapy (1 from each group). These individuals were said to have a more severe presentation.
Selective reporting (reporting bias) Low risk Comment: All specified outcomes were reported.
Other bias High risk Comment: Very small sample.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Comment: Participants were aware of their allocation.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Self‐report measures only, but it is not clear how these were administered.