Parazzini 1998.

Methods	Multicenter study, parallel with cross over. Central telephonic randomization into two arms.
Participants	Participants: 320. Multigravid and primigravid patients. Inclusion criteria: Singleton pregnancies; cephalic presentations; intact membranes; gestation >36 weeks (>40 weeks); Bishop score >4 (5‐7); parity 0‐3; less than six uterine contractions/hour. Exclusion criteria: Previous caesarean section; diabetes; hypertension/PET; ruptured membranes.
Interventions	Intervention 1: Intravenous oxytocin followed in 1 hour by amniotomy (dose 1 mU/m min; rate doubled every 30 min to max 32 mU/min. Intervention 2: Vaginal PGE2 (Prepidil gel, Upjohn 2mg ); two doses at six hourly intervals. Crossover did occur after 12 hours if patients were not in established labour.
Outcomes	Included outcomes: Caesarean section. Uterine hyperstimulation; instrumental vaginal delivery; neonatal intensive care admission; nausea; fever.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate