Table 1.
Clinical Characteristics of the 8 Lean and 8 OIR Participants in the Study
| Lean | OIR | Significance | |
|---|---|---|---|
| (n = 8) | (n = 8) | ||
| Sex (male/female) | 4/4 | 4/4 | NS |
| Race (White/Black) | 5/3 | 4/4 | NS |
| Ethnicity (Hispanic/Non-Hispanic) | 1/7 | 0/8 | NS |
| Age (years) | 27.6 ± 3.1 | 29.1 ± 3.9 | NS |
| BMI (kg m-2) | 22.1 ± 0.7 | 32.2 ± 1.5 | P < 0.001 |
| Body fat (%) | 16.7 ± 3.1 | 27.9 ± 3.2 | P < 0.05 |
| 2-hour OGTT glucose (mg dL-1) | 100 ± 5.3 | 104.7 ± 6.4 | NS |
| HbA1c (%) | 5.1 ± 0.1 | 5.3 ± 0.1 | NS |
| Fasting plasma glucose (mg dL-1) | 86.7 ± 1.0 | 91.2 ± 2.3 | NS |
| Fasting plasma insulin (pmol L-1) | 20.6 ± 3.2 | 40.8 ± 9.7 | P < 0.05 |
| Total Cholesterol (mg dL-1) | 144.8 ± 13.8 | 169.9 ± 10.4 | NS |
| Triglycerides (mg dL-1) | 49.1 ± 5.0 | 89.3 ± 15.3 | P < 0.05 |
| HDL Cholesterol (mg dL-1) | 57.4 ± 5.2 | 43.9 ± 7.2 | NS |
| LDL Cholesterol (mg dL-1) | 77.6 ± 10.9 | 104.5 ± 9.8 | NS |
| M-value (mg kg-1 min-1)* | 10.1 ± 0.8 | 5.5 ± 0.5 | P < 0.001 |
Data are given as mean ± SEM. Abbreviations: BMI, body mass index; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NS, not significant; OGTT, oral glucose tolerance test. *Insulin-stimulated glucose disposal rates (M-value), the average glucose infusion value during the last 30 minute of clamp study.