Table 3.

Brain regions that exhibited significant activation during magnitude presentation in the Alcohol group

Brain region	Cluster size (voxels)	xa	y	z	Z statistic
Alcohol Group
Cluster #1b	7708
Fusiform (L)		−22	−78	−10	6.78
Lingual/calcerine gyri (L)		−14	−86	−8	5.97
Lingual gyrus (R)		22	−76	−8	5.93
Fusiform (R)		26	−60	−12	5.52
Middle occipital gyrus (L)		−14	−100	6	5.43
Cluster #2	1264
Precentral gyrus (L)		−38	−26	62	5.48
Postcentral gyrus (L)		−34	−24	50	5.39
Precentral/middle frontal gyri (L)		−34	−8	58	4.47
Cluster #3	607
Insula (R)		36	26	2	4.76
Insula/inferior frontal gyrus (R)		30	18	8	4.71
Inferior frontal gyrus (R)		83		14	4.47
Cluster #4	494
Supplementary motor area (L/R)			6	56	4.84
Cluster #5	223
Middle/anterior cingulate cortex (L/R)		6	34	32	4.24
Superior medial gyrus/anterior cingulate cortex (L/R)		2	44	26	4.10
Cluster #6	146
Thalamus (L)		−14	−14	6	4.46
Cluster #7	140
Insula (L)		−34	14	−8	4.30
Cluster #8	127
Middle frontal gyrus (R)		42	52	14	4.10
Cluster #9	117
Thalamus (R)
Cluster #10	99	12	−12	10	4.75
Precentral gyrus (R)		46	6	30	4.64

Z-statistic maps were thresholded using cluster-corrected statistics with a height-threshold of Z > 3.1 and cluster-forming threshold of p < 0.05.

^ax, y, z reflect coordinates (mm) for peak voxel or other local maxima in MNI_152 space.

^bClusters are numbered and presented in order of decreasing size.

^cL and R refers to left and right hemisphere.

^*Controlling for age, education, and cigarettes per day