Table 5.

Brain regions that exhibited differences between Control and Alcohol groups during delay presentation

Brain region	Cluster size (voxels)	xa	y	z	Z statistic
Healthy controls > Alcohol group
Cluster #1b	3155
Superior occipital/Calcerine gyri (R)		18	−98	6	7.33
Superior/Middle occipital gyrus (R)		22	−98	6	7.32
Lingual/Inferior occipital/Middle occipital gyri (R)		24	−86	−6	6.20
Inferior occipital gyrus (R)		36	−84	−6	5.83
Cluster #2	3151
Precentral gyrus (L)		−40	−18	56	6.89
Postcentral gyrus (L)		−52	−20	50	524
Cluster #3	2365
Middle occipital gyrus (L)		−20	−98	8	7.17
Inferior occipital/fusiform gyri (L)		−30	−86	−10	6.17
Lingual gyrus (L)		−22	−74	−10	5.54
Cluster #4	1753
Supplementary motor area (SMA) (L/R)		−4	6	50	6.15
Middle cingulate cortex (L/R)		−8	22	38	5.11
Superior medial gyrus/Middle cingulate cortex/SMA (L/R)		4	20	44	5.01
Cluster #5	896
Superior parietal lobule (R)		32	−62	50	5.61
Inferior parietal lobule (R)		40	−42	44	4.77
Middle occipital gyrus (R)		34	−62	38	4.66
Supramarginal gyrus (R)		36	−36	44	4.62
Postcentral gyrus (R)		46	−22	44	4.13
Cluster #6	415
Insula/Putamen (R)		32	22	6	5.26
Insula (R)		36	16	2	4.88
Cluster #7	236
Precentral gyrus (R)		48	4	30	4.61
Inferior frontal gyrus (R)		54	8	28	4.33
Precentral/Middle frontal gyri (R)		54	10	40	3.56
Cluster #8	229
Insula/Inferior frontal gyrus (L)		−34	12	6	4.90
Insula (L)		−28	26	4	3.60
Cluster #9	93
Thalamus (L)		−10	−18	8	4.40
Cluster #10	81
Insula (L)		−42	−2	10	4.36

Z-statistic maps were thresholded using cluster-corrected statistics with a height-threshold of Z > 3.1 and cluster-forming threshold of p < 0.05.

^ax, y, z reflect coordinates (mm) for peak voxel or other local maxima in MNI_152 space.

^bClusters are numbered and presented in order of decreasing size.

^cL and R refers to left and right hemisphere.

^*Controlling for age, education, and cigarettes per day