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. 2019 Dec 27;24(2):1848–1865. doi: 10.1111/jcmm.14881

Figure 1.

Figure 1

Low expression of lncRNA F11‐AS1 might serve as an indicator of poor prognosis in patients with HBV‐related HCC. A, lncRNA F11‐AS1 expression in HBV+/HBV− HCC tissues and corresponding adjacent tissues determined by RT‐qPCR; HBV+ HCC tissues = 45, HBV− HCC tissues = 28. B, lncRNA F11‐AS1 expression in HCC cell lines (Huh7, HepG2, HepG2.2.15, SMMC‐7721) and human normal liver cell line HL‐7702 measured by RT‐qPCR. C, Kaplan‐Meier's analysis of survival rates of patients with HBV+ HCC regarding higher and lower lncRNA F11‐AS1 expression. D, The localization of lncRNA F11‐AS1 in HepG2.2.15 cells detected by FISH assay and qPCR after nuclear/cytoplasmic fractionation (×400). * P < .05 vs adjacent tissues, HBV− HCC tissues or HL‐7702 cell line; # P < .05 vs the HepG2 cell line. Data were measurement data and expressed by mean ± standard deviation. Comparison of data between matched HCC and normal tissues was analysed by paired t test and that between the two groups was analysed by unpaired t test, and that among multiple groups was examined by one‐way analysis of variance followed by Tukey's post hoc test