Figure 5.

DNM1L deficiency attenuates the IL‐1β–induced NF‐κB activation in FLSs. A, The relative levels of AKT, IKK and NFKBIA expression and AKT and IKK phosphorylation were determined by Western blot. B, The nuclear translocation of NF‐κBp65 in the different groups of FLSs was determined by immunofluorescent microscopy. Scale bars: 50 µm. Data are representative images or expressed as the mean ± SD of each group of cells from three separate experiments. *P < .05; **P < .01; ***P < .001; ***P < .0001