Table 2.

Associations between BMI‐1, PTEN, AKT and pAKT expressions and clinicopathological data

Clinicopathological parameter	BMI‐1		PTEN		AKT		pAKT		pAKT/AKT
	Mean ± SD	P‐value	Mean ± SD	P‐value	Mean ± SD	P‐value	Mean ± SD	P‐value	Mean ± SD	P‐value
Normal	0.832 ± 0.115	.606	1.229 ± 0.356	<.0001	0.629 ± 0.062	0.051	1.795 ± 0.438	.093	3.059 ± 0.721	.0029
Cancer	0.752 ± 0.068		0.525 ± 0.105		0.701 ± 0.111		4.208 ± 0.974		17.43 ± 4.683
Grade
1	1.027 ± 0.190	.233	0.458 ± 0.092	.711	0.645 ± 0.164	0.661	4.639 ± 1.085	.142	5.775 ± 1.344	.860
2	0.714 ± 0.086		0.628 ± 0.182		0.736 ± 0.176		3.511 ± 0.727		13.91 ± 3.231
3	0.665 ± 0.131		0.352 ± 0.071		0.674 ± 0.187		2.129 ± 0.688		10.08 ± 3.021
Stage
I	0.867 ± 0.104	.0094 a	0.594 ± 0.175	.866	0.620 ± 0.105	0.386	5.465 ± 1.683	.0015 b	13.34 ± 2.679	.073
II	0.826 ± 0.133		0.477 ± 0.188		0.781 ± 0.222		1.845 ± 0.466		7.457 ± 1.806
III + IV	0.435 ± 0.072		0.408 ± 0.077		0.496 ± 0.134		0.771 ± 0.216		5.952 ± 2.112
Lymph node metastasis
No	0.826 ± 0.078	.005	0.552 ± 0.128	.710	0.582 ± 0.087	0.105	4.730 ± 1.158	.021	5.375 ± 1.086	.015
Yes	0.393 ± 0.083		0.394 ± 0.107		1.274 ± 0.478		1.695 ± 0.770		2.252 ± 0.252

Kruskal‐Wallis test was used to compare more than two groups. For pairwise multiple comparisons the Dunn's post hoc test was used.

Bold values show statistically significant differences.

^aI vsIII + IV, II vs III + IV.

^bI vsIII + IV, II vs III + IV.