Figure 1.

The expression landscape of circulating exosome‐derived lncRNAs in HCC patients. A, Expression of CD9, CD63, TSG101 and calnexin by Western blot. The expression of CD9, CD63, TSG101 and calnexin in isolated exosomal pellets from the sera of patients were compared with those of the supernatant. The expression of CD9, CD63, and TSG101 was present in the isolated exosomes, whereas calnexin, a negative marker of exosomes, was only expressed in the supernatant. B, Cluster analysis of the different expression of the lncRNAs in different groups. NC: normal control; CH: chronic hepatitis; HCC‐N: HCC without metastasis; HCC‐M: HCC with metastasis