Figure 1.

LASP1 is up‐regulated in HNSCC and associated with a poor prognosis. A, The difference in LASP1 expression between HNSCC tissues and normal adjacent tissues based on data from the UALCAN database (P < .001). B, The relationship between LASP1 expression and patient survival time based on data from the human protein Atlas database (P < .05). C, Real‐time PCR analysis of the mRNA expression of LASP1 in 40 pairs of HNSCC tissue specimens and the corresponding adjacent normal tissues (P = .0058). D, The representative IHC images of LASP1 expression in the well‐, moderately and poorly differentiated HNSCC tissues and adjacent normal tissues. E. Real‐time PCR and Western blot were used to detect the mRNA and protein expression levels of LASP1 in five HNSCC cell lines and PDLC cells (P < .001)