Table 1.

Associations between LASP1, HSPA1A mRNA levels and clinical parameters in a training cohort (n = 40)

	LASP1 mRNA expression (2−ΔΔCt Mean ± SD)	P value	HSPA1A mRNA expression (2−ΔΔCt Mean ± SD)	P value
Age (y)
≥60	0.3265 ± 0.1363	.2016	0.1729 ± 0.04684	.2667
<60	0.1234 ± 0.04475		0.11 ± 0.02279
Gender
Man	0.1494 ± 0.04484	.2027	0.1118 ± 0.02075	.7833
Women	0.4351 ± 0.2367		0.2211 ± 0.07715
Smoking history
Yes	0.1624 ± 0.0649	.4799	0.1494 ± 0.03399	.8963
No	0.2787 ± 0.1197		0.1417 ± 0.04018
T stage
T1‐T1	0.2461 ± 0.09555	.7836	0.1404 ± 0.02746	.7686
T3‐T4	0.1912 ± 0.09698		0.1613 ± 0.09072
Lymph node metastasis
pN positive	0.2781 ± 0.1277	.0482	0.1733 ± 0.04422	.2605
pN negative	0.1826 ± 0.08048		0.1095 ± 0.0296
TNM stage
I–II	0.1431 ± 0.07442	.0174	0.1138 ± 0.03107	.3487
III–IV	0.3031 ± 0.1245		0.1673 ± 0.04267
Perineural invasion
Yes	0.1324 ± 0.03466	.3984	0.1016 ± 0.0202	.3488
No	0.2791 ± 0.1107		0.1609 ± 0.03745
ECS
Yes	0.1108 ± 0.04467	.5560	0.111 ± 0.04269	.6544
No	0.2529 ± 0.08923		0.1494 ± 0.03134
Prior radiotherapy
Yes	0.1181 ± 0.06172	.5381	0.1241 ± 0.0168	.7621
No	0.2557 ± 0.09149		0.1482 ± 0.03271

The mRNA expression of LASP1 in head and neck tumour tissues was associated with lymph node metastasis (P = .0482) and TNM stage (P = .0174), but not with age, gender or smoking history. The mRNA expression of HSPA1A was not associated with any clinical parameters.