Figure 3.

LncRNA ZFAS1 promotes tumour formation in nude mice. A, Growth curve of the tumour xenograft formed by HONE1 cells in nude mice. HONE1 cells were pre‐transfected with ZFAS1‐targeting shRNA (shZFAS1) or p‐ZFAS1, and tumour volumes were measured every 3 days. *P < .01 compared with the NC group by two‐way ANOVA followed by Bonferroni post‐tests. Scale bar: 1 cm. B, Schematic representation of tumour xenografts. Animals were killed after implantation for 21 days, and tumour xenografts were harvested and imaged. C, Weight comparison of the harvested tumour xenografts. D, Expression level of ZFAS1 in the xenografts. *P < .05, **P < .01 and ***P < .001