Comparison 5. Nitrates vs ACE inhibitors.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Total Serious Adverse Events	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2 All‐cause mortality	1	46	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Non‐fatal cardiovascular events	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
4 Myocardial Infarction	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Respiratory insufficiency requiring mechanical ventilation	1	46	Risk Ratio (M‐H, Fixed, 95% CI)	0.33 [0.01, 7.78]
5.1 Nitrates vs. ACE‐I	1	46	Risk Ratio (M‐H, Fixed, 95% CI)	0.33 [0.01, 7.78]
6 Withdrawals due to adverse effects	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
7 Mean change in systolic blood pressure during treatment	1	46	Mean Difference (IV, Fixed, 95% CI)	3.33 [‐7.37, 14.03]
7.1 Nitrogycerine vs Enalaprilat	1	46	Mean Difference (IV, Fixed, 95% CI)	3.33 [‐7.37, 14.03]
8 Mean change in diastolic blood pressure during treatment	1	46	Mean Difference (IV, Fixed, 95% CI)	‐0.33 [‐6.69, 6.03]
8.1 Nitrogycerine vs Enalaprilat	1	46	Mean Difference (IV, Fixed, 95% CI)	‐0.33 [‐6.69, 6.03]
9 Mean change in heart rate during treatment	1	46	Mean Difference (IV, Fixed, 95% CI)	4.5 [‐1.18, 10.18]
9.1 Nitrogycerine vs Enalaprilat	1	46	Mean Difference (IV, Fixed, 95% CI)	4.5 [‐1.18, 10.18]