Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 30;15(1):e0227279. doi: 10.1371/journal.pone.0227279

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

PMC Copyright notice

Fig 1 — (A) Western blotting on hBMSCs from three different individuals (D01, D02, D03), transduced with LV-Ctr (C), LV- Gsα^R201C (R) showing the expression of the exogenously provided mutant Gsα^R201C as highlighted by immunoblotting with anti-HA and anti-Gsα antibodies. 1.4 fold change on Gsα band in LV- Gsα^R201C (R) respect to that transduced with LV-Ctr (C) has been calculated as the average, on duplicates. (B) Relative values for GNAS expression in D01, D02, D03, transduced with LV-Ctr (ctr) or LV- Gsα^R201C (R201C) showing the expression of the exogenously provided mutant Gsα^R201C. 1.6 fold change on Gsα RNA expression has been calculated as the fold change on the average of triplicate samples from LV- Gsα^R201C and LV-Ctr samples. (C) Hierarchical clustering of modulated genes in triplicate samples of hBMSCs from three different individuals (D01, D02, D03), transduced with LV-Ctr (C), LV- Gsα^R201C (R) or mock-treated (M). (D) Total number of significantly modulated genes (threshold: 2.5). Up-regulated genes are indicated in red, down-regulated in green.