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. 2020 Jan 30;15(1):e0228258. doi: 10.1371/journal.pone.0228258

Table 4. Nutritional and micronutrient status among non-pregnant women of reproductive age, Ghana 2017.

National Urban Rural p-value c
Characteristic N % / Mean a 95%CI b N %/ Mean 95%CI N %/ Mean 95%CI
Nutritional status d
    BMI, mean 1003 24.5 (24.1; 25.0) 438 25.8 (25.2; 26.4) 565 23.3 (22.9; 23.8) <0.001
    Severely undernourished, % 1002 0.5 (0.2; 1.2) 437 0.6 (0.2; 1.9) 565 0.4 (0.1; 1.7) 0.63
    Moderately undernourished, % 1002 1.3 (0.8; 2.2) 437 0.9 (0.4; 2.3) 565 1.7 (0.9; 3.1) 0.26
    At risk for undernutrition, % 1002 6.2 (4.6; 8.2) 437 4.3 (2.8; 6.7) 565 8.0 (5.6; 11.2) <0.05
    Normal, % 1002 53.0 (48.6; 57.4) 437 44.6 (38.9; 50.4) 565 61.1 (55.2; 66.7) <0.001
    Overweight, % 1002 24.7 (21.0; 28.8) 437 29.7 (23.5; 36.9) 565 19.8 (16.2; 24.0) <0.01
    Obese, % 1002 14.3 (11.5; 17.7) 437 19.8 (15.4; 25.2) 565 9.0 (6.9; 11.7) <0.001
Micronutrient status
Hemoglobin concentration
    Hemoglobin (g/L), mean 999 127.6 (126.4; 128.9) 436 127.9 (125.8; 130.1) 563 127.3 (125.6; 128.7) 0.62
    Any anemia, % 999 21.7 (18.7; 25.1) 436 21.6 (17.5; 26.4) 563 21.8 (17.4; 26.8) 0.96
    Moderate anemia, % 999 7.0 (5.1; 9.5) 436 8.2 (5.7; 11.7) 563 5.8 (3.4; 9.8) 0.29
    Severe anemia, % 999 0.4 (0.2; 1.3) 436 0.9 (0.3; 2.5) 563 - - 0.05
Iron status
    Ferritin (μg/L), median (IQR) e 987 43.1 (23.3; 72.4) 438 40.4 (19.2; 72.2) 549 44.3 (27.3; 72.4) <0.05
    Iron deficiency, % f 987 13.7 (11.2; 16.6) 438 15.7 (12.5; 19.7) 549 11.7 (8.3; 16.1) 0.15
    Iron deficiency anemia, % 989 8.9 (6.7; 11.7) 435 9.8 (7.2; 13.2) 554 8.0 (4.8; 12.9) 0.48
Vitamin A status
    RBP (μmol/L), mean g 987 1.64 (1.59; 1.70) 438 1.62 (1.56; 1.68) 549 1.66 (1.57; 1.76) 0.49
    Vitamin A deficiency, % h 987 1.5 (0.8; 2.9) 438 1.1 (0.4; 2.8) 549 1.9 (0.8; 4.4) 0.40
Folate status
    Serum folate, median (IQR) 473 9.3 (5.4; 16.4) 211 9.3 (4.9; 17.0) 262 9.4 (5.5; 15.3) 0.89
    Folate deficiency, % i 473 53.8 (47.6; 60.0) 211 55.5 (48.4; 62.3) 262 52.2 (42.3; 62.0) 0.60
Vitamin B12 status
    Serum vitamin B12, mean 471 454.0 (426.8; 481.3) 210 471.4 (426.8; 516.1) 261 437.0 (402.3; 471.8) 0.23
    Vitamin B12 deficiency j, % 471 6.9 (4.8; 9.8) 210 6.4 (3.8; 10.7) 261 7.4 (4.5; 11.9) 0.70
    Vitamin B12 marginal j, % 471 11.9 (9.0;15.6) 210 10.4 (6.3; 16.7) 261 13.4 (9.9; 17.8) 0.38

a Percentages/means weighted for unequal probability of selection.

b CI = confidence interval, calculated taking into account the complex sampling design. For median calculations, inter-quartile range is provided.

c P-values measuring the differences in mean and prevalence between urban and rural areas was calculated using t-test and chi-square test; the Mann-Whitney test was used to calculate p-values between medians.

d Severe undernutrition defined as BMI <16.0; moderate undernutrition defined as BMI 16.0–16.9; at risk of undernutrition defined as BMI 17.0–18.5; normal BMI defined as BMI 18.5–24.9; overweight defined as BMI 25.0–29.9; obese defined as BMI >30.

e Adjusted for inflammation [20]; corresponding unadjusted median ferritin concentration 45.9 μg/L (IQR: 25.0; 83.7).

f Based on inflammation-adjusted ferritin concentration [20].

g Retinol-binding protein, adjusted for inflammation [22]; corresponding unadjusted mean RBP concentration 1.65 μmol/L (95%CI: 1.59; 1.71).

h Based on the retinol-binding protein, adjusted for inflammation [22].

i Folate deficiency defined as serum folate <10 nmol/L; this analyte was measured only in a random sub-sample of women.

j Vitamin B12 deficiency and marginal status defined as plasma B12 <148 pmol/L & plasma B12 ≥148 & <220; this analyte was measured only in a random sub-sample of women.