Table 4. PFTs before and after pirfenidone therapy in stable and progressive group.

Variable Mean±SD	Stable disease (n = 34)		Progressive disease (n = 7)
	Baseline value	Post treatment	Baseline value	Post treatment
FVC (% predicted)	68.6±13.5a	66.7±12.8a	60.0±10.6c	48.6±9.6c
DLco (% predicted)	44.5±12.9b	43.2±14.0b	42.3±16.1d	31.6±12.1d
ΔFVC (% predicted)	-2.0±5.0e		-11.5±6.3e
ΔDLco (% predicted)	-1.3±5.4f		-10.7±6.9f

^a: P = 0.542

^b: P = 0.689

^c: P = 0.055

^d: P = 0.185

^e: P<0.001

^f: P<0.001

ΔFVC, ΔDLco = the mean change in FVC or DLco from baseline to the end of follow-up

FVC = forced vital capacity; DLco = diffusion capacity of carbon monoxide.