Table 3 Cardiopulmonary exercise testing reference values in persons with mild to moderate Alzheimer’s disease who reached criteria for VO 2 max.
| Women | Men | |||||
|---|---|---|---|---|---|---|
| Yes | No | Yes | No | |||
| Subjects | 19 | 22 | 26 | 30 | ||
| Age | 77.3 (7.1) | 77.4 (5.4) | 75.5 (7.3) | 78.8 (6.6) | ||
| MMSE | 22.8 (3.3) | 20.9 (3.5) | 21.1 (3.8) | 21.5 (3.1) | ||
| BMI | 29.3 (5.7) | 28.5 (5.1) | 28.5 (5.2) | 28.5 (5.4) | ||
| Test Duration (min) | 8.6 (2.6) | 8.9 (3.9) | 13.3 (3.2) | 11.5 (2.8) | ||
| Watts | 92.4 (32.3) | 94.3 (28.0) | 129.9 (34.5) | 115.2 (39.6) | ||
| HR peak (bpm) | 130.3 (10.7)* | 114.6 (13.1) | 127.5 (17.4)* | 106.2 (14.4) | ||
| %APMHR Peak | 0.93 (.09)* | 0.80 (0.1) | 0.87 (.13)* | 0.75 (0.10) | ||
| RPE peak | 16.8 (1.2)* | 14.6 (1.9) | 16.2 (1.9)* | 14.9 (2.4) | ||
| METS peak | 5.9 (1.6) | 6.2 (1.2) | 7.2 (1.4)* | 6.4 (1.3) | ||
| V E peak (L/min) | 41.7 (7.3) | 38.7 (7.0) | 59.2 (13.7)* | 46.3 (11.1) | ||
| RR peak (breaths/min) | 33.0 (8.4) | 31.7 (6.6) | 29.7 (4.4) | 26.9 (4.8) | ||
| V T peak (V E /RR) | 1.3 (.3) | 1.2 (.2) | 2.0 (.5)* | 1.7 (.4) | ||
| VO 2 Peak (L/min) | 1.05 (.21) | 1.06 (.19) | 1.48 (.38) | 1.31 (.31) | ||
| VO 2 Peak (ml/kg/min) | 16.0 (4.2) | 15.6 (3.3) | 19.5 (5.1)* | 16.3 (3.4) | ||
| VCO 2 Peak (L/min) | 1.18 (.26) | 1.07 (.18) | 1.74 (.60) | 1.41 (.36) | ||
| VCO 2 Peak (ml/kg/min) | 17.8 (4.7) | 16.0 (4.2) | 22.9 (7.0)* | 17.3 (4.6) | ||
| RER Peak | 1.11 (.09) | 1.05 (.11) | 1.17 (.11)* | 1.05 (.08) | ||
| EqVO 2 Peak | 40.1 (7.7) | 37.3 (6.2) | 40.7 (6.2)* | 35.8 (4.7) | ||
| EqVCO 2 Peak | 36.2 (7.1) | 36.2 (4.2) | 35.1 (6.1) | 34.5 (4.4) | ||
| O 2 Pulse Peak (ml/beat) | 7.9 (1.6)* | 9.2 (1.4) | 12.0 (2.8) | 12.5 (3.0) | ||
| VO 2 / Work Rate Peak (ml/min/W) | 11.9 (3.3) | 11.7 (3.4) | 11.9 (1.8) | 11.9 (2.4) | ||
Values are expressed as means (SD). *Significantly different from individuals (within the same sex with CVD) (P=0.05). MMSE, Mini-Mental State Examination; BMI, body mass index; HR, heart rate; APMHR, age-predicted max heart rate; RPE, rating of perceived exertion; METS, metabolic equivalent of task; V E , minute ventilation; RR, respiratory rate; V T , tidal volume; VO 2 , volume of oxygen consumed; VCO 2 , volume of carbon dioxide produced; RER, respiratory exchange ratio; EqVO 2, ventilatory equivalents oxygen; EqVCO 2 , ventilatory equivalents carbon dioxide; O 2 Pulse, oxygen pulse.