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. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Nat Microbiol. 2020 Jan 20;5(2):256–264. doi: 10.1038/s41564-019-0645-9

Figure 4. The conjugation efficiency of ESBL-encoding plasmids from human commensal E. coli to ciprofloxacin-resistant Shigella sonnei with and without supplementation with ciprofloxacin.

Figure 4

Boxplots showing the conjugation frequencies (log10) between five commensal E. coli isolates and cipR S. sonnei strain 03-0520 with and without supplementing conjugation media with 0.25x, 0.5x, and 0.75x MIC of the donor cipS commensal E. coli. Each conjugation experiment was performed in triplicate in each condition. Boxes represent the interquartile range, with the internal line indicating the data median. Maxima and minima shown extend from the box +/- 1.5*IQR, with data falling outside of that range shown as points (n = 3 biologically independent experiments, 3 technical replicates of each).