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. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Nat Microbiol. 2020 Jan 20;5(2):256–264. doi: 10.1038/s41564-019-0645-9

Extended Data Figure 3. Root-to-tip regression for the maximum likelihood tree of Shigella sonnei in Vietnam, 2014-2016.

Extended Data Figure 3

Each point on the plot corresponds to a measurement of genetic distance from the inferred root to each tip in the tree (n = 81 biologically independent samples). The solid line is the regression line fitted using the ordinary least squares method. The slope of the line is a crude estimate of the evolutionary rate, the x-intercept corresponds to the inferred date of the most recent common ancestor, and the R2 value measures the degree of clock-like behavior.