Table 2.
OCT measures and letter-acuity scores by group.
| AQP4-ON | MOG-ON | MS-ON | HC | |
|---|---|---|---|---|
| OCT measures, μm, mean (SD) | ||||
| Global pRNFLa | 67.5 (15.6) | 60.9 (11.2) | 78.9 (11.5) | 91.3 (10.0) |
| Superior quadranta | 80.4 (23.5) | 72.8 (16.3) | 100.6 (19.4) | 114.2 (15.3) |
| Nasal quadranta | 60.0 (10.3) | 56.9 (7.4) | 65.3 (8.8) | 71.5 (12.1) |
| Inferior quadranta | 80.8 (30.5) | 74.3 (18.6) | 102.2 (19.2) | 119.7 (17.7) |
| Temporal quadranta | 48.6 (12.3) | 39.8 (10.6) | 47.3 (10.6) | 60.1 (10.0) |
| GCIPLb | 54.9 (10.9) | 56.5 (6.5) | 64.3 (10.4) | 75.9 (4.7) |
| INLb | 43.9 (4.0) | 44.6 (3.7) | 44.7 (4.7) | 45 (2.5) |
| ONLb | 65.9 (5.6) | 69.6 (5.9) | 69.2 (6.0) | 69 (6.2) |
| Letter-acuity scoresc, median (IQR) | ||||
| 100% contrast (HCLA) | 43.5 (0-54.5) | 57 (53-60) | 59 (50-64) | 60 (58-65) |
| 2.5% contrast (LCLA) | 0 (0-19.5) | 11 (3-15) | 28 (14-34) | 33.5 (28-36) |
a
Available for 65 AQP4-ON, 27 MOG-ON, 47 MS-ON and 60 HC eyes
b
Available for 69 AQP4-ON, 27 MOG-ON, 47 MS-ON and 59 HC eyes
c
Available for 56 AQP4-ON, 21 MOG-ON, 47 MS-ON and 58 HC eyes
Abbreviations: ON: optic neuritis; AQP4-ON: aquaporin-4-IgG seropositive ON; MOG-ON: myelin oligodendrocyte glycoprotein-IgG seropositive ON; MS-ON: multiple sclerosis ON; HC: healthy control; SD: standard deviation; IQR: inter-quartile range; OCT: optical coherence tomography; pRNFL: peri-papillary retinal nerve fiber layer; GCIPL: ganglion cell+inner plexiform layer; INL: inner nuclear layer; ONL: outer nuclear layer; HCLA: high-contrast letter-acuity; LCLA: low-contrast letter acuity