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Magnetic source images show the locations of generalized spike-wave discharges (GSWDs) in patients at 30–80, 80–250, and 250–500 Hz. At the 80–250 Hz, medial frontal cortex (MFC) are always activated during ictal GSWDs, while during interictal GSWDs, the locations are almost in the deep brain area (DBA). There are more DBA locations during interictal GSWDs when comparing with ictal GSWDs at 250–500 Hz. The yellow arrows show the differences between the two groups.
