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There was significant difference in the functional connectivity (FC) [posterior cingulate cortex (PCC)/precuneus (pC) as the region of interest (ROI)] between interictal and ictal generalized spike-wave discharges (GSWDs) at 80–250 Hz. Interictal GSWDs had FC almost exclusively in the posterior cortex, whereas ictal GSWDs had strong connections in the anterior-posterior pathways (mainly with the frontal cortex).
