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. 2020 Jan 24;10:917. doi: 10.3389/fendo.2019.00917

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Copyright © 2020 Esteves, Yarali, Ubaldi, Carvalho, Bento, Vaiarelli, Cimadomo, Özbek, Polat, Bozdag, Rienzi and Alviggi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blastocyst euploidy probability per mature (MII) oocyte. The plots show the probability of an MII oocyte turn into a euploid blastocyst as a function of female age and sperm source. The estimated probabilities (solid curves) and their 95% CI (dotted curves) are presented according to sperm source for IVF/ICSI, namely, ejaculated sperm (blue) and testicular sperm extracted from patients with non-obstructive azoospermia (NOA) (red). The relations are non-linear and characterized by a differential modulatory effect of sperm source across age (see text).