Table 2.
Final validation model for prediction of the probability (p) of euploid blastocyst per mature (MII) oocyte.
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Y = −2.728414 –0.138868 [I(spermSource=Ejaculate) – I(spermSource=Testicular_NOA)] −0.13032 [I(spermSource=Testicular_NOA) – I(spermSource=NOA)] +0.4928267[I(spermSource = Ejaculate) – I(spermSource=Testicular NOA)] +0.0807783[I(Center = Anatolia) – I(Center = Androfert)] +0.3765617[I(Center = GENERA) – I(Center = Anatolia)] Where the indicator function I(x) = 1 if x is TRUE and 0 otherwise. The probability p is | ||||||
| Term | Estimate | Std error | Wald ChiSquare | Prob > ChiSquare | Lower 95% | Upper 95% |
| Intercept (a) | −2.728414 | 0.183 | 220.281 | <0.0001 | −3.088 | −2.368 |
| spermSource[Ejaculate-Testicular_NOA]:(ageFemale-39.414) | −0.138868 | 0.007 | 306.601 | <0.0001 | −0.154 | −0.123 |
| spermSource[Testicular_NOA-NOA]:(ageFemale-39.414) | −0.13032 | 0.027 | 22.471 | <0.0001 | −0.184 | −0.076 |
| spermSource[Ejaculate-Testicular NOA] | 0.4928267 | 0.179 | 7.570 | 0.006 | 0.141 | 0.843 |
| Center [Anatolia-Androfert] | 0.0807783 | 0.105 | 0.591 | 0.441 | −0.125 | 0.286 |
| Center [GENERA-Anatolia] | 0.3765617 | 0.068 | 30.010 | <0.0001 | 0.241 | 0.511 |
| Response: euploid blastocyst per MII oocytes | –LogLikelihood: 1527.242 | |||||
| Distribution: negative binomial | Number of Parameters: 6 | |||||
| Estimation method: adaptive Lasso | BIC: 3,098.065 | |||||
| Validation method: AICc | AICc: 3,066.544 | |||||
| Probability model link: Logit | Generalized RSquare: 0.258 | |||||
| Number of rows: 1,464 | Area under the curve: 0.700 | |||||
The full equation is written at the top of the table. Each particular characteristic is displayed with an associated P-value (Prob >ChiSquare) giving the indication of how much weight each variable will contribute to the probability of blastocyst euploidy per metaphase II oocytes.