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. 2020 Jan 24;10:3065. doi: 10.3389/fimmu.2019.03065

Figure 7.

Figure 7

Unique ILCs respond to cytokine stimulation. C10, C2, and cNKs were stimulated with PMA/Ionomycin, IL-12/IL-15/IL-1β, or IL-12/IL-15/IL-18 and production of (A) INFγ, (B) Granzyme B, (C) TNFα, and (D) VEGF was assessed. Data represented as max/min, median, and 25 and 75th percentiles. Statistical significance was determined by ANOVA followed by Tukey test and are demonstrated by letters, with different letters indicating statistical differences within a subset (<0.05). Additionally, comparisons across subsets within tissues were performed, for simplicity p-values are found in Supplementary Table 10. For (A–C, unstim and PMA/Ionomycin): Decidua basalis, n = 24; decidua parietalis, n = 9. For (A–C, IL12/IL15/IL1β): Decidua basalis, n = 19; decidua parietalis, n = 7 (A–C, IL12/IL15/IL18): Decidua basalis, n = 7. For (D, unstim, PMA/Ionomycin, IL12/IL15/IL1β): Decidua basalis, n = 13; decidua parietalis, n = 3. For (D, IL12/IL15/IL18): Decidua basalis, n = 7. N.A = not analyzed. For statistical details see Supplementary Table 10. Data is provided in Data Sheet 1.