Figure 3.
The knockdown of AC091729.7 inhibits the proliferation, migration, and invasion of SNSCC cells. (A) Relative RNA level of AC091729.7 was decreased in SNSCC cells with AC091729.7 knockdown. (B) CCK-8 showed that the viability of SNSCC cells was inhibited after the downregulation of AC091729.7 expression. (C) Colony-formation assay suggested that SNSCC cell proliferation was inhibited after AC091729.7 knockdown. (D) Subcutaneous xenograft SNSCC tumors developed in nude mice after RPMI-2650 cells were transfected with lentivirus encoding (a) AC091729.7 shRNA; (b) control shRNA. (E) Wound healing cell migration assay. (F) Transwell invasion assay (**p < 0.01).