Table 3.
Model variable | Nerves per cm2 of thyroid tissue | Nerves per cm2 of PTC | ||
---|---|---|---|---|
Beta coefficient | p-value | Beta coefficient | p-value | |
Age | 0 (0 to 0) | 0.27 | 0 (0 to 0) | 0.77 |
Sex | −0.2 (−0.7 to 0.3) | 0.33 | −0.2 (−0.7 to 0.3) | 0.42 |
Tumour size (cm) | −0.3 (−0.5 to 0) −27% (−44 to −10%) | 0.003 | −0.5 (−0.8 to −0.4) −55% (−74 to −36%) | <0.0001 |
Extra-thyroidal invasion | 0.8 (0.3 to 1.3) 123% (41 to 250%) | 0.001 | 1.1 (0.6 to 1.6) 209% (87 to 411%) | <0.0001 |
Multifocality | 0 (−0.4 to 0.5) | 0.84 | 0 (0 to 0.2) | 0.96 |
Nodal metastases | −0.1 (−0.6 to 0.4) | 0.78 | −0.3 (−0.8 to 0.3) | 0.34 |
Intercept | 3.3 (2.4 to 4.1) | 3.9 (2.9 to 4.8) |
Multiple log-linear regression of log-transformed nerve density and untransformed markers of cancer aggressiveness in PTCs. Coefficients (95% CI) are reported. Percentage change of the untransformed variable is co-reported (italics) for significant model variables, where each 1 unit increase in the model variable is associated with a percentage change in nerve density.