Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 30;11(1):77. doi: 10.1038/s41419-020-2280-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — a Representative immunoblots of mitochondrial fission proteins (P-DRP1 and FIS1) in the mitochondrial fraction from cortical tissue of P9 WT and AIF Tg mice under physiological conditions. Quantification of P-DRP1 and FIS1 did not show a significant difference between WT and AIF Tg mice (n = 6/group). b Representative immunoblots of mitochondrial fusion proteins (OPA1 and MFN1) in the mitochondrial fraction from cortical tissue of P9 WT and AIF Tg mice under physiological conditions. Quantification of OPA1 and MFN1 did not show any significant difference between WT and AIF Tg mice (n = 6/group). c Immunoblotting of P-DRP1and FIS1 in the mitochondrial fraction from the cortical tissue of the CL and IL hemispheres in WT and AIF Tg mice at 24 h after HI. Quantification of P-DRP1 and FIS1 did not show any significant differences in the CL and IL hemispheres between WT and AIF Tg mice (n = 6/group). d Immunoblotting of OPA1 and MFN1 in the mitochondrial fraction from cortical tissue of the CL and IL hemispheres at 24 h after HI in WT and AIF Tg mice. The expression of MFN1 was significantly decreased at 24 h post-HI both in WT and AIF Tg mice, while the short form (82 kDa) and cleavage band of OPA1 were significantly increased at 24 h post-HI in both the WT and AIF Tg mice. Quantification of OPA1 and MFN1 did not show any significant differences in the CL and IL hemispheres between WT and AIF Tg mice (n = 6/group).