Table 1.
List of articles which evaluated M1 and M2 TAMs in tissue sections from 2014 to 2019.
| References | Cancer type | Staining type | Markers |
|---|---|---|---|
| Jeong et al. (23) | Invasive breast cancer | IHC | CD68/CD11c—M1 CD 68/CD163—M2 |
| Sousa et al. (68) | Breast cancer | IHC | CD68—pan macrophage HLA-DRα–M1 CD163—M2 |
| Rakaee et al. (66) | Non-small cell lung cancer (NSCLC) | IHC | HLA-DR/CD68—M1 CD163/CD68—M2 CD204/CD68—M2 |
| Almatroodi et al. (63) | Non-small cell lung cancer (NSCLC) | IHC | CD68—pan macrophage iNOS—M1 CD163—M2 |
| Shu et al. (69) | Hepatocellular carcinoma | IHC | CD68—pan macrophage CD11c—M1 CD206—M2 |
| Dong et al. (21) | Hepatocellular carcinoma | IHC | CD68—pan macrophage CD86—M1 CD206—M2 |
| Dumars et al. (64) | Osteosarcoma | IHC | CD68—pan macrophage iNOS—M1 CD163—M2 |
| Lúcio et al. (70) | Squamous cell carcinomas of the lower lip | IHC | CD68—pan macrophage HLA-DR—M1 CD163—M2 |
| Lin et al. (71) | Pulmonary squamous cell carcinomas | IHC | pSTAT1—M1 CD163—M2 |
| Xu et al. (72) | Renal cell carcinoma | IHC | CD68—pan macrophage CD11c—M1 CD206—M2 |
| Kelly et al. (73) | Type 2 endometrial cancer | IHC | CD68—total TAMs CD163—M2 TAMs |
| Petrillo et al. (39) | Locally Advanced Cervical Cancer (LACC) | IHC | CD68/pSTAT—M1 CD68/cMAF—M2 CD163/pSTAT—M1 CD163/cMAF—M2 |
| Marchesi et al. (65) | Diffuse large B-cell lymphoma | IF | CD68/HLA-DR—M1 CD68/CD163—M2 |
| Yu et al. (74) | Extrahepatic cholangiocarcinoma | IF | CD14—pan macrophage CD14+CD163–:M1 CD14+CD163+ :M2 |
| Lee et al. (75) | Sonic hedgehog (SHH) medulloblastomas | IHC for macrophage recruitment | CD68—pan macrophage CD86—M1 CD163—M2 |
| IF to confirm localization | CD86—M1 CD163—M2 |
||
| Zhang et al. (40) | Ovarian cancer | IHC for macrophage recruitment | CD68—pan macrophage |
| IF to confirm localization | CD68—pan macrophage iNOS—M1 HLA-DR—M1 CD163—M2 VEGF—M2 |
||
| Mori et al. (76) | Oral squamous cell carcinoma | IHC for macrophage recruitment | CD68—pan macrophage CD80—M1 CD163—M2 |
| IF to confirm localization | STAT1/pSTAT1—M1 CD163—M2 |