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. 2020 Jan 30;10:1482. doi: 10.1038/s41598-020-58547-w

Table 3.

Subgroup analysis of crude and adjusted hazard ratios (95% confidence interval) of sudden sensory neural hearing loss in depression according to age and sex in study I.

Characteristics HRs of SSNHL
Crude P-value Adjusted†‡ P-value
Young men (20–39 years old, n = 33,400)
Depression 1.17 (0.71–1.93) 0.531 0.99 (0.60–1.64) 0.967
Control I 1.00 1.00
Young women (20–39 years old, n = 63,715)
Depression 1.20 (0.85–1.70) 0.311 1.08 (0.76–1.53) 0.688
Control I 1.00 1.00
Middle aged men (40–59 years old, n = 40,510)
Depression 1.39 (1.00–1.92) 0.047* 1.22 (0.88–1.70) 0.229
Control I 1.00 1.00
Middle aged women (40–59 years old, n = 78,620)
Depression 1.54 (1.25–1.90) <0.001* 1.36 (1.10–1.68) 0.005*
Control I 1.00 1.00
Old men (60 + years old, n = 29,615)
Depression 1.05 (0.69–1.58) 0.832 0.92 (0.61–1.40) 0.709
Control I 1.00 1.00
Old women (60 + years old, n = 57,730)
Depression 1.24 (0.86–1.47) 0.386 1.03 (0.79–1.34) 0.836
Control I 1.00 1.00

*Cox-proportional hazard regression model, Significance at P Co0.05.

Stratified model for age, sex, income, and region of residence.

Adjusted model for Charlson Comorbidity Index.