Table 6.
Multivariate logistic regression analysis result of factors associated with amputation among diabetic foot ulcer patients admitted to NRH, west Ethiopia, 2018.
| Variables | Amputation |
COR(95%CI) | P value | AOR(95%CI) | P value | ||
|---|---|---|---|---|---|---|---|
| Amputated n (%) |
Not Amputated n (%) |
||||||
| Residence | Rural | 17(29.82) | 40(70.18) | 1.720[0.392,7.554] | 0.247* | 1.547[0.364,6.579] | 0.416 |
| Urban | 18(31.03) | 40(68.97) | 1 | 1 | |||
| Sex | Male | 19(29.69) | 45(70.31) | 1.639[0.169,2.410] | 0.158* | 1.660[0.178,2.451] | 0.221 |
| Female | 16(31.37) | 35(68.63) | 1 | 1 | |||
| Drinking Alcohol Currently | Yes | 12(31.58) | 26(68.42) | 1.516[0.107,2.485] | 0.240* | 1.594[0.128,2.761] | 0.693 |
| No | 23(29.87) | 54(70.13) | 1 | 1 | |||
| Smoking cigarette currently | Yes | 12(40) | 18(60) | 1.426[0.362,5.622] | 0.188* | 1.359[0.346,5.345] | 0.222 |
| No | 23(27.06) | 62(72.94) | 1 | 1 | |||
| Previous history of Ulcer | Yes | 16(32.65) | 33(67.35) | 1.656[0.175,2.462] | 0.235* | 1.674[0.182,2.499] | 0.317 |
| No | 19(28.79) | 47(71.21) | 1 | 1 | |||
| Types of DM | Type 2 DM | 23(37.70) | 38(62.30) | 1.483[0.117,2.001] | 0.074* | 1.431[0.108,1.715] | 0.057 |
| Type 1 DM | 12(22.22) | 42(77.78) | 1 | 1 | |||
| Hypertension | Yes | 16(28.57) | 40(71.43) | 2.951[0.216,4.186] | 0.167* | 1.109[0.267,4.604] | 0.509 |
| No | 19(32.20) | 40(67.80) | 1 | 1 | |||
| Ischemic Heart Disease | Yes | 14(34.15) | 27(65.85) | 1.184[0.298,4.708] | 0.152* | 1.133[0.345,5.156] | 0.361 |
| No | 21(28.38) | 53(71.62) | 1 | 1 | |||
| Dyslipidaemia | Yes | 13(32.50) | 27(67.50) | 2.645[0.141,2.937] | 0.157* | 1.766[0.185,3.170] | 0.629 |
| No | 22(29.33) | 53(70.67) | 1 | 1 | |||
| Retinopathy | Yes | 17(30.90) | 38(69.10) | 1.345[0.092,1.386] | 0.113* | 1.358[0.097,1.319] | 0.052 |
| No | 18(30) | 42(70) | 1 | 1 | |||
| Neuropathy | Yes | 20(38.46) | 32(61.54) | 2.658[1.561,12.602] | 0.029* | 1.565[1.508,4.822] | 0.004** |
| No | 15(23.81) | 48(76.19) | 1 | 1 | |||
| Coronary Heart Disease | Yes | 9(33.33) | 18(66.67) | 1.176[0.035,2.891] | 0.078* | 1.179[0.135,1.915] | 0.179 |
| No | 26(29.55) | 62(70.45) | 1 | 1 | |||
| Nephropathy | Yes | 18(39.13) | 28(60.87) | 1.645[0.148,2.814] | 0.100* | 1.227[0.173,3.013] | 0.604 |
| No | 17(24.64) | 52(75.36) | 1 | 1 | |||
| Peripheral Vascular Disease | Yes | 13(30.95) | 29(69.05) | 1.243[0.283,5.452] | 0.177* | 1.440[0.343,6.048] | 0.864 |
| No | 22(30.14) | 51(69.86) | 1 | 1 | |||
| Body mass index | <24.5 | 15(23.08) | 50(76.92) | 1 | 0.073* | 1 | 0.122 |
| 24.5–29.5 | 12(35.29) | 22(64.71) | 7.054[1.410,35.296] | 0.032* | 2.767[1.827,9.252] | 0.021** | |
| >29.5 | 8(50) | 8(50) | 7.729[2.828,72.134] | 0.017* | 3.020[2.556,16.397] | 0.019** | |
| Glycaemic Control | Poor Control | 21(39.62) | 32(60.38) | 2.779[1.755,10.231] | 0.048* | 2.592[1.937,7.168] | 0.023** |
| Good Control | 14(22.58) | 48(77.42) | 1 | 1 | |||
| Duration of Diabetic Mellitus | <5years | 14(33.33) | 28(66.67) | 1 | 0.184* | 1 | 0.174 |
| 5–10years | 14(29.79) | 33(70.21) | 2.273[0.299,5.418] | 0.071* | 1.171[0.279,4.910] | 0.061 | |
| >10years | 7(26.92) | 19(73.08) | 1.672[0.112,4.011] | 0.157* | 1.596[0.103,3.439] | 0.558 | |
| Size of Ulcer | <1 cm2 | 16(24.24) | 50(75.76) | 1 | 0.215* | 1 | 0.109 |
| 1–5 cm2 | 11(42.31) | 15(57.69) | 1.515[0.109,2.431] | 0.190* | 1.608[0.139,2.665] | 0.253 | |
| >5 cm2 | 8(34.78) | 15(65.22) | 1.881[0.154,5.027] | 0.132* | 1.894[0.158,5.054] | 0.130 | |
| Appropriateness of Antibiotics | Inappropriate | 21(53.85) | 18(46.15) | 6.192[1.108,34.614] | 0.012* | 2.526[1.767,8.314] | 0.017** |
| Appropriate | 14(36.84) | 24(63.16) | 1 | 1 | |||
| Grade of Ulcer | Grade <4 |
19(21.84) | 68(78.16) | 1 | 0.001* | 1 | 0.005** |
| Grade ≥4 |
16(57.14) | 12(42.86) | 3.209 [1.790,13.033] | 1.70[1.604,4.789] | |||
Note *Shows statistically significant p-value ≤0.25 at 95% CI.
**Shows statistically significant p-value ≤0.05 at 95% CI.